MPP6 Antibody

Catalog Number:

40288

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NZW5
Gene Accssion:NP_057531

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MPP6 protein.

Applications:

IHC

Background:

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).

References:

appl_detail:

Immunohistochemistry:1:30-1:150

Datasheet PDF