Product Datasheet
MPP6 Antibody
Catalog Number: 40288
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9NZW5
Gene Accssion:NP_057531
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
- appl_detail:
-
Immunohistochemistry:1:30-1:150
- other_names:
- VAM1; p55T; PALS2; VAM-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MPP6 protein.
- Background:
- Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).
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