SORT1 Antibody

Catalog Number:

40218

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q99523
Gene Accssion:NP_002950

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human sortilin 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SORT1 protein.

Applications:

WB IHC

Background:

This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry:1:35-1:150

Datasheet PDF