HCRT Antibody

Catalog Number:

40204

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O43612
Gene Accssion:NP_001515

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human hypocretin (orexin) neuropeptide precursor

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HCRT protein.

Applications:

WB

Background:

This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF