Product Datasheet
HCRT Antibody
Catalog Number: 40204
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O43612
Gene Accssion:NP_001515
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human hypocretin (orexin) neuropeptide precursor
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- OX; PPOX; NRCLP1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HCRT protein.
- Background:
- This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.
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