ORAI1(L1) Antibody

Catalog Number:

40190

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q96D31
Gene Accssion:NP_116179

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human ORAI calcium release-activated calcium modulator 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ORAI1(L1) protein.

Applications:

WB

Background:

The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).?

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF