Product Datasheet
ORAI1(L1) Antibody
Catalog Number: 40190
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q96D31
Gene Accssion:NP_116179
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide of human ORAI calcium release-activated calcium modulator 1
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- IMD9; TAM2; ORAT1; CRACM1; TMEM142A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ORAI1(L1) protein.
- Background:
- The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).?
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