THAP4 Antibody

Catalog Number:

40142

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8WY91
Gene Accssion:BC000247

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human THAP domain containing 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total THAP4 protein.

Applications:

IHC

Background:

Human THAP4 is a 577 residue protein of unknown function that is proposed to bind DNA in a sequence specific manner similar to THAP1 and has been found to be upregulated in response to heat shock.THAP4 is expressed in a relatively uniform manner in a broad range of tissues and appears to be upregulated in lymphoma cells and highly expressed in heart cells13. The C-terminal domain of THAP4 (residues 415-577), designated here as cTHAP4, is evolutionarily conserved and is observed in all know THAP4 orthologues. Several single domain proteins lacking a THAP domain are found in plants and bacteria, and show significant levels of homology to cTHAP4. It appears that cTHAP4 belongs to a large class of proteins that have yet to be fully functionally characterized.

References:

appl_detail:

Immunohistochemistry: 1:100-1:200

Datasheet PDF