Product Datasheet  
THAP4 Antibody  
Catalog Number: 40142  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q8WY91
    Gene Accssion:BC000247
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to residues near the C terminal of human THAP domain containing 4
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:100-1:200
  • other_names:  
  • PP238; CGI-36
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total THAP4 protein.
  • Applications:  
  • IHC
  • Background:  
  • Human THAP4 is a 577 residue protein of unknown function that is proposed to bind DNA in a sequence specific manner similar to THAP1 and has been found to be upregulated in response to heat shock.THAP4 is expressed in a relatively uniform manner in a broad range of tissues and appears to be upregulated in lymphoma cells and highly expressed in heart cells13. The C-terminal domain of THAP4 (residues 415-577), designated here as cTHAP4, is evolutionarily conserved and is observed in all know THAP4 orthologues. Several single domain proteins lacking a THAP domain are found in plants and bacteria, and show significant levels of homology to cTHAP4. It appears that cTHAP4 belongs to a large class of proteins that have yet to be fully functionally characterized.



 
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