ST18 Antibody

Catalog Number:

40120

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O60284
Gene Accssion:BC117147

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human suppression of tumorigenicity 18, zinc finger

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ST18 protein.

Applications:

IHC

Background:

ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells.?

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF