Product Datasheet
ST18 Antibody
Catalog Number: 40120
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O60284
Gene Accssion:BC117147
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human suppression of tumorigenicity 18, zinc finger
- appl_detail:
-
Immunohistochemistry:1:25-1:100
- other_names:
- NZF3; ZNF387; ZC2HC10
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ST18 protein.
- Background:
- ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid nuclear protein that is expressed at low levels in heart, liver, kidney, skeletal muscle, pancreas, testis, ovary and prostate. Containing six C2HC-type zinc fingers and an SMC domain, ST18 is a repressor protein that binds to DNA sequences containing a specific bipartite element. ST18 is considered a transcription factor that represses basal transcription activity from target promoters and Inhibits colony formation in cultured breast cancer cells.?
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