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PEG10 Monoclonal Antibody

Catalog Number:

27129
other_names: EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

Amount:

100μg
calculated_mw:
host_species: Mouse

Price:

$369

Swiss-Prot No:

Swiss-Prot:P27361
Gene ID:5595

Form of Antibody:

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Storage/Stability:

Immunogen:

Purified recombinant human PEG10 protein fragments expressed in E.coli.

Purification:

Affinity purified

Specificity/Sensitivity:

Applications:

ELISA WB IP

Background:

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation.

References:

appl_detail:

Predicted MW: 55kd
Western blotting: 1:1000

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