Product Datasheet
PEG10 Monoclonal Antibody
Catalog Number: 27129
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P27361
Gene ID:5595
- Form of Antibody:
- Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
- Immunogen:
- Purified recombinant human PEG10 protein fragments expressed in E.coli.
- appl_detail:
- Predicted MW: 55kd
Western blotting: 1:1000
- other_names:
- EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3
- Purification:
- Affinity purified
- Applications:
- ELISA WB IP
- Background:
- This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation.
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