NUMBL antibody

Catalog Number:

38379

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y6R0
NCBI Gene ID: 9253

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant protein of human NUMBL.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total NUMBL antibody.

Applications:

WB

Background:

Numb-like (Numbl or Nbl) binds Notch and is an intracellular modulator of Notch signaling pathway. Numbl contains a phosphotyrosine binding (PTB) domain that could bind the Y682 motif present in the cytoplasmic tail of APP. Deduced molecular weight of Numbl is 72 kDa.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF