Product Datasheet
NUMBL antibody
Catalog Number: 38379
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y6R0
NCBI Gene ID: 9253
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Recombinant protein of human NUMBL.
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- CAG3A; CTG3a; NBL; NUMB-R; NUMBLIKE; NUMBR; TNRC23;
- Purification:
- Antibodies were purified by affinity purification using immunogen.
- Specificity:
- The antibody detects endogenous level of total NUMBL antibody.
- Background:
- Numb-like (Numbl or Nbl) binds Notch and is an intracellular modulator of Notch signaling pathway. Numbl contains a phosphotyrosine binding (PTB) domain that could bind the Y682 motif present in the cytoplasmic tail of APP. Deduced molecular weight of Numbl is 72 kDa.
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