VCAM1 antibody

Catalog Number:

38123

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P19320
NCBI Gene ID: 7412

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant Protein of human VCAM1.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total VCAM1 antibody.

Applications:

WB,IHC

Background:

Vascular cell adhesion protein 1 (VCAM1) is important in cell-cell recognition. It has been reported to function in leukocyte-endothelial cell adhesion, interact with the beta-1 integrin VLA4 on leukocytes, and mediate both adhesion and signal transduction. There are two isoforms; Isoform 1, a single-pass type I membrane protein, and isoform 2, a lipid-anchor (GPI-anchor). VCAM1 is expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. It is also expressed in the bone marrow (1).

References:

appl_detail:

WB 1:1000 - 1:3000
IHC 1:50 - 1:200
IP 1:50 - 1:200

Datasheet PDF