Product Datasheet
VCAM1 antibody
Catalog Number: 38123
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P19320
NCBI Gene ID: 7412
- Form of Antibody:
- Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Recombinant Protein of human VCAM1.
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:1000 - 1:3000
IHC 1:50 - 1:200
IP 1:50 - 1:200
- other_names:
- VCAM1; L1CAM; VCAM 1; V CAM 1; DKFZp779G2333; CD106
- Purification:
- Antibodies were purified by affinity purification using immunogen.
- Specificity:
- The antibody detects endogenous level of total VCAM1 antibody.
- Background:
Vascular cell adhesion protein 1 (VCAM1) is important in cell-cell recognition. It has been reported to function in leukocyte-endothelial cell adhesion, interact with the beta-1 integrin VLA4 on leukocytes, and mediate both adhesion and signal transduction. There are two isoforms; Isoform 1, a single-pass type I membrane protein, and isoform 2, a lipid-anchor (GPI-anchor). VCAM1 is expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. It is also expressed in the bone marrow (1).
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