SLIT2 Antibody

Catalog Number:

37951

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O94813
NCBI Gene ID: 9353
Gene Accssion: NP_004778/O94813

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human slit homolog 2 (Drosophila)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLIT2 protein.

Applications:

IHC

Background:

Slit homolog 2 protein?is a?protein?that in humans is encoded by the?SLIT2?gene. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF