Product Datasheet  
SLIT2 Antibody  
Catalog Number: 37951  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O94813
    NCBI Gene ID: 9353
    Gene Accssion: NP_004778/O94813
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human slit homolog 2 (Drosophila)
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Immunohistochemistry: 1:25-1:100
  • other_names：  
  • SLIL3; Slit-2
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total SLIT2 protein.
  • Applications：  
  • IHC
  • Background：  
  • Slit homolog 2 protein?is a?protein?that in humans is encoded by the?SLIT2?gene. In spinal chord development may play a role in guiding commissural axons once they reached the floor plate by modulating the response to netrin. In vitro, silences the attractive effect of NTN1 but not its growth-stimulatory effect and silencing requires the formation of a ROBO1-DCC complex. May be implicated in spinal chord midline post-crossing axon repulsion. In vitro, only commissural axons that crossed the midline responded to SLIT2.



 
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