PLXNA4 Antibody

Catalog Number:

37835

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9HCM2
NCBI Gene ID: 91584
Gene Accssion: NP_001099013/Q9HCM2

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human plexin A4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PLXNA4 protein.

Applications:

IHC

Background:

Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF