Product Datasheet  
PLXNA4 Antibody  
Catalog Number: 37835  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: Q9HCM2
    NCBI Gene ID: 91584
    Gene Accssion: NP_001099013/Q9HCM2
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human plexin A4
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • Immunohistochemistry: 1:50-1:200
  • other_names：  
  • PLEXA4; PLXNA4A; PLXNA4B; FAYV2820; PRO34003
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total PLXNA4 protein.
  • Applications：  
  • IHC
  • Background：  
  • Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.



 
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