PPARGC1A Antibody

Catalog Number:

37818

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UBK2
NCBI Gene ID: 10891
Gene Accssion: NP_037393/Q9UBK2

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PPARGC1A protein.

Applications:

WB

Background:

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination.?

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF