Product Datasheet
PPARGC1A Antibody
Catalog Number: 37818
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UBK2
NCBI Gene ID: 10891
Gene Accssion: NP_037393/Q9UBK2
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1(alpha)
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PPARGC1A protein.
- Background:
- The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination.?
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