AQP2 Antibody

Catalog Number:

36759

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P41181
NCBI Gene ID: 359
Gene Accssion: NP_000477

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human Aquaporin-2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AQP2 protein.

Applications:

IHC

Background:

The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF