Product Datasheet
AQP2 Antibody
Catalog Number: 36759
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P41181
NCBI Gene ID: 359
Gene Accssion: NP_000477
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human Aquaporin-2
- appl_detail:
- Immunohistochemistry: 1:100-1:300
- other_names:
- AQP-2; AQP-CD; AQP2; MGC34501
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AQP2 protein.
- Background:
- The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell.
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