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CEP97 Antibody

Catalog Number:

36345
other_names: LRRIQ2; 2810403B08Rik

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q8IW35
NCBI Gene ID: 79598
Gene Accssion: BC041085

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human centrosomal protein 97kDa

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CEP97 protein.

Applications:

WB IHC

Background:

Centrosomal protein of 97 kDa?(Cep97), also known as?leucine-rich repeat and IQ domain-containing protein 2?(LRRIQ2), is a?protein?that in humans is encoded by the?CEP97?gene. Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome. Interacts with CALM1, CEP76 and CCP110. Via its interaction with CCP110, may indirectly interact with HERC2 and NEURL4. Interacts with KIF24.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

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