Product Datasheet
CEP97 Antibody
Catalog Number: 36345
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q8IW35
NCBI Gene ID: 79598
Gene Accssion: BC041085
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human centrosomal protein 97kDa
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
- other_names:
- LRRIQ2; 2810403B08Rik
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CEP97 protein.
- Background:
- Centrosomal protein of 97 kDa?(Cep97), also known as?leucine-rich repeat and IQ domain-containing protein 2?(LRRIQ2), is a?protein?that in humans is encoded by the?CEP97?gene. Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome. Interacts with CALM1, CEP76 and CCP110. Via its interaction with CCP110, may indirectly interact with HERC2 and NEURL4. Interacts with KIF24.
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