BCAT1 Antibody

Catalog Number:

36276

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P54687
NCBI Gene ID: 586
Gene Accssion: NP_005495

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human branched chain amino-acid transaminase 1, cytosolic

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BCAT1 protein.

Applications:

WB IHC

Background:

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Datasheet PDF