XPO1 Antibody

Catalog Number:

36228

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O14980
NCBI Gene ID: 7514
Gene Accssion: BC032847

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human exportin 1 (CRM1 homolog, yeast)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total XPO1 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Datasheet PDF