Product Datasheet
XPO1 Antibody
Catalog Number: 36228
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14980
NCBI Gene ID: 7514
Gene Accssion: BC032847
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human exportin 1 (CRM1 homolog, yeast)
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
- other_names:
- emb; CRM1; exp1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total XPO1 protein.
- Background:
- The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.?
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