MYLK3 Antibody

Catalog Number:

36204

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q32MK0
NCBI Gene ID: 91807
Gene Accssion: BC109097

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human myosin light chain kinase 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MYLK3 protein.

Applications:

IHC

Background:

YLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF