Product Datasheet  
MYLK3 Antibody  
Catalog Number: 36204  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q32MK0
    NCBI Gene ID: 91807
    Gene Accssion: BC109097
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to residues near the N terminal of human myosin light chain kinase 3
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:25-1:100
  • other_names:  
  • MLCK; MLCK2; caMLCK
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total MYLK3 protein.
  • Applications:  
  • IHC
  • Background:  
  • YLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.



 
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