Product Datasheet
MYLK3 Antibody
Catalog Number: 36204
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q32MK0
NCBI Gene ID: 91807
Gene Accssion: BC109097
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human myosin light chain kinase 3
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- MLCK; MLCK2; caMLCK
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MYLK3 protein.
- Background:
- YLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.
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