MAP4K2 Antibody

Catalog Number:

36189

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q12851
NCBI Gene ID: 5871
Gene Accssion: BC047865

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human mitogen-activated protein kinase kinase kinase kinase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAP4K2 protein.

Applications:

WB

Background:

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.?

References:

appl_detail:

Western blotting: 1:1000-1:5000

Datasheet PDF