INSIG2 Antibody

Catalog Number:

36556

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y5U4
NCBI Gene ID: 51141
Gene Accssion: BC022475

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human insulin induced gene 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total INSIG2 protein.

Applications:

IHC

Background:

The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF