Product Datasheet  
INSIG2 Antibody  
Catalog Number: 36556  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9Y5U4
    NCBI Gene ID: 51141
    Gene Accssion: BC022475
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to a region derived from internal residues of human insulin induced gene 2
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:25-1:100
  • other_names:  
  • INSI2;INSIG2 membrane protein; insulin induced protein 2
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total INSIG2 protein.
  • Applications:  
  • IHC
  • Background:  
  • The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.



 
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