ACTR1A Antibody

Catalog Number:

36031

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P61163
NCBI Gene ID: 10121
Gene Accssion: BC000693

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ACTR1A protein.

Applications:

WB

Background:

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF