Product Datasheet  
ACTR1A Antibody  
Catalog Number: 36031  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P61163
    NCBI Gene ID: 10121
    Gene Accssion: BC000693
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to residues near the C terminal of human ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • Western blotting: 1:200-1:1000
  • other_names:  
  • ARP1; CTRN1
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total ACTR1A protein.
  • Applications:  
  • WB
  • Background:  
  • This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.



 
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