Product Datasheet
ACTR1A Antibody
Catalog Number: 36031
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P61163
NCBI Gene ID: 10121
Gene Accssion: BC000693
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
- appl_detail:
- Western blotting: 1:200-1:1000
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ACTR1A protein.
- Background:
- This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
© Signalway Biotechnology All Rights Reserved.