TPH1 Antibody

Catalog Number:

35965

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P17752
NCBI Gene ID: 7166
Gene Accssion: BC106739

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human tryptophan hydroxylase 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TPH1 protein.

Applications:

IHC

Background:

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF