Product Datasheet  
TPH1 Antibody  
Catalog Number: 35965  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: P17752
    NCBI Gene ID: 7166
    Gene Accssion: BC106739
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Fusion protein corresponding to residues near the C terminal of human tryptophan hydroxylase 1
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:15-1:50
  • other_names:  
  • TPRH; TRPH
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total TPH1 protein.
  • Applications:  
  • IHC
  • Background:  
  • This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.



 
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