LTA Antibody

Catalog Number:

35964

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P01374
NCBI Gene ID: 4049
Gene Accssion: BC034729

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human lymphotoxin alpha (TNF superfamily, member 1)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LTA protein.

Applications:

IHC

Background:

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF