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PAX8 Antibody

Catalog Number:

35870
other_names: paired box 8;Paired box protein Pax-8; paired domain gene 8

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q06710
NCBI Gene ID: 7849
Gene Accssion: BC001060

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human Paired box 8

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PAX8 protein.

Applications:

WB IHC

Background:

This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50

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