Product Datasheet
PAX8 Antibody
Catalog Number: 35870
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q06710
NCBI Gene ID: 7849
Gene Accssion: BC001060
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human Paired box 8
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
- other_names:
- paired box 8;Paired box protein Pax-8; paired domain gene 8
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PAX8 protein.
- Background:
- This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.?
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