KLRC1 Antibody

Catalog Number:

35839

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P26715
NCBI Gene ID: 3821
Gene Accssion: BC053840

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human killer cell lectin-like receptor subfamily C, member 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KLRC1 protein.

Applications:

IHC

Background:

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF