Product Datasheet
KLRC1 Antibody
Catalog Number: 35839
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P26715
NCBI Gene ID: 3821
Gene Accssion: BC053840
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human killer cell lectin-like receptor subfamily C, member 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- NKG2; NKG2A; CD159A
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KLRC1 protein.
- Background:
- Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.
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