ATF2 Antibody

Catalog Number:

35647

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P15336
NCBI Gene ID: 1386
Gene Accssion: BC130335

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human activating transcription factor 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATF2 protein.

Applications:

IHC

Background:

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF