Product Datasheet
ATF2 Antibody
Catalog Number: 35647
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P15336
NCBI Gene ID: 1386
Gene Accssion: BC130335
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human activating transcription factor 2
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- HB16; CREB2; TREB7; CRE-BP1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ATF2 protein.
- Background:
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene.?
© Signalway Biotechnology All Rights Reserved.