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PLCgamma1(Phospho-Tyr783) Antibody

Catalog Number:

15103
other_names: Phosphoinositide phospholipase C; Phospholipase C-gamma-1;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P19174
NCBI Protein: NP_002651.2

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 783 (G-F-Y(p)-V-E) derived from Human PLCG1.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Specificity/Sensitivity:

The antibody detects endogenous level of PLCg1 only when phosphorylated at tyrosine 783.

Applications:

WB

Background:

PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

DeBell KE, et al. Mol Cell Biol. 1999 Nov; 19(11): 7388-7398.
Ver

References:

appl_detail:

Predicted MW: 155kd
Western blotting: 1:500~1:1000
 

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