Product Datasheet  
PLCgamma1(Phospho-Tyr783) Antibody  
Catalog Number: 15103  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: P19174
    NCBI Protein: NP_002651.2
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
  • Immunogen：  
  • Peptide sequence around phosphorylation site of tyrosine 783 (G-F-Y(p)-V-E) derived from Human PLCG1.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Predicted MW: 155kd
    Western blotting: 1:500~1:1000
     

  • other_names：  
  • Phosphoinositide phospholipase C; Phospholipase C-gamma-1;
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Specificity：  
  • The antibody detects endogenous level of PLCg1 only when phosphorylated at tyrosine 783.
  • Applications：  
  • WB
  • Background：  

  • PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

    DeBell KE, et al. Mol Cell Biol. 1999 Nov; 19(11): 7388-7398.
    Ver




 
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