ADAM17 Antibody

Catalog Number:

36043

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P78536
NCBI Gene ID: 6868
Gene Accssion: BC062687

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ADAM17 protein.

Applications:

IHC

Background:

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.?

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF