Product Datasheet
ADAM17 Antibody
Catalog Number: 36043
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P78536
NCBI Gene ID: 6868
Gene Accssion: BC062687
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Full length fusion protein
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- CSVP; TACE; NISBD; ADAM18; CD156B
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ADAM17 protein.
- Background:
- This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.?
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